Severe adverse events are rare but are closely monitored in clinical trials
As a gut hormone, its activity corresponds to the food we eat: (GLP-1) levels rise in our body maybe two to three fold when we eat a meal. Certain types of food especially fats and fatty acids are better at promoting GLP-1 release, Drucker continued
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But the drug, formerly known as Accutane, can have some serious side effects
Although the observed increase in risk is small on an individual level, the broad adoption of GLP1-RAs for weight management amplifies its potential implications at the population level, underscoring the need for heightened awareness among clinicians and patients about the dermatologic effects of these medications, the authors wrote
Weight regain after stopping is a documented pattern with all GLP-1 class compounds, and Retatrutide is expected to follow the same pattern