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They are proof of it

Wound Repair Regen 13:452461

Glycolysis can be reutilized in the mitochondria Mitochondria Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes

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Cancer acceleration poses the greatest long-term threat

The observed upregulation of not only the ThDP-dependent dehydrogenases limiting and feeding the TCA cycle, but also the thiamine transporters and ThDP-producing enzyme TPK1 (Figures 4B, 5B), may compensate for decreased levels and/or increased demands of thiamine in enterocytes 69 months after gastric bypass, facilitated by the higher expression of the proteins binding thiamine or ThDP