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Synthesis and release of gonadotropins are regulated by neuroendocrine signals from the central nervous system

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iii) cardiovascular pathologies such as heart failure, congenital diseases and cardiovascular malformations, as well as pathologies with genetic determinism (Brugada syndrome, long QT, arrhythmogenic dysplasia of the right ventricle), chronic ischemic heart disease, hypertension, myocarditis, pericarditis, vascular disease, electric pacemaker devices

He Z, et al

Patients must provide informed consent acknowledging the off-label, evidence-limited nature of this therapy

For others, genetic data confirms that microdosing or standard semaglutide will deliver optimal results