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JW: Writing review & editing, Methodology, Formal analysis, Funding acquisition, Project administration, Conceptualization

Nonetheless, challenges such as undefined optimal dosing, delivery routes, treatment schedules, and long-term safety uncertainties must be resolved before clinical translation

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Rhodiola rosea provides another example, with salidroside and rosavin enhancing mitochondrial ATP production, improving oxygen utilization, and stabilizing monoamine neurotransmitters under stress (189, 190)

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