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Cytotoxicity Assay The assessment of the hepatoprotective effect of SAG was performed using the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide (MTT) reduction assay [42]

Introduction The liver is the major organ metabolizing xenobiotics and endogenous molecules in order to maintain metabolic homeostasis in the organism, which is why it is a target of many toxic substances that cause dysregulated hepatic homeostasis

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Preliminary clinical investigations suggest that Yerba Mat may exert beneficial effects on weight management through multiple mechanisms, including pancreatic lipase inhibition, modulation of gastric motility, and enhancement of energy expenditure (20, 21)

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The tapering of therapy should be slow, with a 25% to 50% dose reduction every 3 to 4 weeks