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Event adjudication committee-confirmed CV outcomes were assessed in the two metformin subgroups: time to first MACE (composite of three-components: CV death, non-fatal MI or non-fatal stroke)the primary outcome

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Glucagon-Like Peptide I Stimulates Insulin Gene Expression and Increases Cyclic AMP Levels in a Rat Islet Cell Line

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GLP-1 (glucagon-like peptide-1) is an incretin hormone that stimulates insulin secretion, slows gastric emptying, and reduces appetite