This is typically a localized skin reaction and does not necessarily indicate an internal issue
Insufficient DAO commonly occurs with gut inflammation, certain genetic variants, or medications that inhibit DAO activity
PubMed , World Journal of Gastroenterology , vol
In addition, vitamin C's three magic properties (antioxidant, collagen booster, skin brightener) are all properly proven in-vivo (on real people), but for the derivatives, it's mostly in-vitro studies or in the case of THDA, it's in-vitro and done by an ingredient supplier
(Tirzepatide differential receptor affinities) Frias JP, et al
ma dire che produce meno disturbi intestinali del tirzepatide non supportato dai dati del confronto diretto