Even when vision improves, some deficit often remains
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That distinction guides treatment and support, which may include hearing devices, therapy for tinnitus, or lifestyle changes that address vascular or metabolic contributors
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It is not an FDA-approved drug for systemic therapeutic use
Several factors explain the lack of approval: insufficient clinical trials (no completed Phase 3 trials for most indications), safety concerns (FDA has identified specific adverse events), commercial considerations (patent status affects development investment), regulatory pathway (approval requires specific, rigorous documentation), and competition (Tesamorelin already approved for related indication)