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gossypii , DARPP is exposed by a reduction reaction and a subsequent deamination by corresponding enzymes DARPP reductase (encoded by RIB7 ) and DArPP deaminase (encoded by RIB2 ), to generate 5-amino-6-ribityl-amino-2,4(1H,3H)pyrimidinedione 5-phosphate (ArPP) (Figure 1)

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