Reapply throughout the day as needed, especially on dry or pigmented areas
Going back to the IEL cells for a moment, in Crohns disease and ulcerative colitis (UC) these cells can start to attack the gut lining itself, this further creates a cytotoxic environment, which can further exacerbate IELs to produce pro-inflammatory proteins, this can lead to a compromised intestinal lining, along with alterations in the gut microbiome
Pelttari, K., Wixmerten, A
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J Med Chem 53 : 31833197
