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However, the absence of a direct interaction does not guarantee optimal outcomes

Sibarov et al

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Discussion In this study, we have demonstrated for the first time that inhibition of both the ligand and the receptor of the HGF/c-MET pathway (using a neutralising antibody against HGF and a small-molecule c-MET receptor inhibitor) in combination with a chemotherapeutic agent (gemcitabine), that is, (triple therapy, Hi + Ci + G) significantly reduced tumour size and, more importantly, completely eradicated metastasis in a clinically relevant advanced pancreatic cancer model

The PlexusDx Precision Peptide Genetic Test reveals these predispositions, allowing your provider to weigh whether GLP-1 therapy, compounded tirzepatide dual-receptor activation, or alternative strategies align better with your biology and surgical history