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The Mayo Clinic suggests that although vitamin C supplements may reduce the levels of uric acid in your blood, no studies have demonstrated that the severity or frequency of gout flares are affected by vitamin C

References References Heffernan M, et al

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Some individuals experience mild gastrointestinal effects including nausea or abdominal discomfort, particularly with higher doses or when first initiating therapy

The relationship between SHs and the GH/IGF-1 axis is well known since many years