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Bettermann et al

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Migraine manifests as recurrent bouts of moderate to severe headache lasting between 4 to 72 h, typically one-sided, and accompanied by nausea, sensitivity to light (photophobia), sensitivity to sound (phonophobia), and/or vomiting (6, 7)

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Folate is important for brain and nervous system development, which is why pregnant women are often prescribed supplements that contain folic acid, a synthetic version of folate

With GSH depleted, IKK becomes constitutively active, driving continuous transcription of TNF-, IL-6, and IL-1