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Intestinal absorptive capacity, intestinal permeability and jejunal histology in HIV and their relation to diarrhoea
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Despite current limitations in counteracting cancer cachexia due to its complex pathogenesis and lack of targeted agents, BPC157, a pentadecapeptide, shows promising potential as a fundamental agent targeting the signaling processes implicated in cancer cachexia
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After three months of intragastric Dihexa administration (1.44 or 2.88 mg/kg), the APP/PS1 mice showed restored Morris water maze performance, increased neuronal cell counts and synaptophysin expression on Nissl staining, reduced microglial and astrocyte activation, decreased pro-inflammatory cytokines (IL-1, TNF-) and increased anti-inflammatory IL-10
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