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44 Indeed, third-generation formulations have been developed recently and these formulations include curcumin galactomannan formulation or CurQfen (noncovalent complex between curcumin and fenugreek galactomannans), curcuRouge (Starch and curcumin formulation), Curcuwin Ultra (cellulosic derivatives and curcumin formulation), and Longvida (soy lecithin and curcumin formulation) (Figure 2)

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AMPK phosphorylation was suppressed, and autophagy activity was inhibited in high-glucose cultured human renal proximal epithelial cells (HRPTCs) and STZ-induced diabetic nephropathy mice

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