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In this case, a vicious cycle can happen where increased insulin levels drive an increase in glucose SGLT2 overexpression increasing glycemic levels which in turn will increment the insulin secretion (Figure 4C)

Muscle contractility is determined by measuring the force of contraction caused by stimulation of frequency 10 Hz compared to the force of contraction caused by stimulation of frequency 100 Hz (maximum contraction force)

doi: 10.1002/jssc.200700261 82 FernandesAJDFerreiraMRARandauKPde SouzaTPSoaresLAL