This show is all about applying evidenced-based and effective dietary lifestyle and natural health product strategies for your optimal health
On the data side, the Lau phase 2 obesity trial showed Cagrilintide monotherapy producing dose-related weight loss, reaching close to 10.8 percent at the top dose over roughly 26 weeks, against about 3 percent on placebo
J Am Soc Nephrol (2004) 15(8):213951
The incidence of acute pancreatitis with GLP-1 receptor agonist therapy in individuals with a known history of pancreatitis
As an interesting result, a study using triple-knockout mice lacking cystathionine -synthase, cystathionine -lyase, and 3-mercaptopyruvate sulfurtransferase revealed that supersulfides were still produced, suggesting the existence of compensatory or alternative synthetic pathways for supersulfide generation (24)
Dose adjustments and close monitoring of kidney function are essential