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Targeting metabolism, insulin resistance, and diabetes to treat nonalcoholic steatohepatitis

It could also become an ethical issue

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It also requires more additional support from our interdisciplinary team, too, as we have these patients not only coming to us for medicine, but having them also engage with our other team members for our [lifestyle intervention]. Nguyen said monitoring safety and efficacy of obesity drugs in the adolescent population will be a focus of future quality improvement projects.

It is worth mentioning that ME or AP GLP-1R-expressing neurons may mediate the anorexic effect of peripheral GLP-1RA administration directly, without allowing the drugs entering the brain region furtherly