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SIRT1 modulates lipid metabolism in the liver through the upregulation of PPAR [60]

Multimodal treatments tailored to different clinical presentations and potential underlying pathogenic mechanisms are recommended by current guidelines

Similarly, in the NAFLD mouse model, mice fed with a high-fat diet showed reduced hepatic GLP-1R expression, which was reversed by NaB treatment and accompanied by markedly alleviated liver steatosis