Low Starting Amount Amount per injection: 2.5 mg 50 units (0.50 mL) on a U-100 insulin syringe Frequency: Once daily, under the skin (subcutaneous) Cycle length: One 5 mg vial = 2 days at the starting amount Sources: [1] Selective small-molecule inhibitors of NNMT reverse high-fat-diet-induced obesity in mice PubMed
The enzyme slows down how the body breaks down fat cells
NAD plays a central role in cellular repair and mitochondrial function
This results in fast-acting nutrient delivery, making the vitamins more available for your body to use immediately This is especially important for people who: Have digestive issues like IBS or Crohns disease Have undergone gastric bypass or other stomach surgeries Have difficulty absorbing nutrients through the gut Fast-acting nutrient delivery ensures your body gets what it needswithout waiting for the digestive system to process it
As of June 2026, the FDA's December 2024 Pharmacy Compounding Advisory Committee evaluation concluded that the criteria weighed against placing AOD-9604 (free base) or AOD-9604 acetate on the 503A Bulks List, and AOD-9604 is currently listed as Nominated but Withdrawn from FDA Category 2
The best approach starts with bloodwork so you know where your levels actually sit