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Capitalizing on this understanding, nutritional interventions target OA through a multi-tiered approach: (1) Upstream regulation using anti-inflammatory nutrients (e.g., omega-3 fatty acids, polyphenols) to quell systemic inflammation and oxidative stress (10)

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Introduction Since its first clinical use in 1950, acetaminophen (N-acetyl-p-aminophenol, APAP) has remained a widely used antipyretic and analgesic

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If consuming enough omega-3 rich food like salmon, additional supplementation may not be necessary 2