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Reporter protein-targeted probes for magnetic resonance imaging

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Its binding to VMAT2 is very strong, making it's effect appear irreversible, with trace amounts of the drug remaining bound to vesicular membranes for many days, and its clinical effects lasting many days to weeks, and may persist until new transporter proteins are synthesized (German et al, 2015

41,42 In addition, Wang et al 43 confirmed that ER stress decreases the eNOS phosphorylation and the generation of NO in rats aortic endothelial cells, which can be reversed by ER stress inhibitors