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We first validated our measurements of insulin sensitivity and insulin secretion in a separate sample of 287 non-diabetic individuals not belonging to the METSIM cohort

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Furthermore, our findings seem translationally promising, given recent reports that semaglutide reduces alcohol cravings in humans (29) and that exenatide diminishes cue reactivity in AUD patients (30)

But severity differs

Consequently, while in agreement with many years of biochemical findings, the model for catalase action suggested here will attempt to augment current thinking about its mechanism