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A selective and augmentable butyrate-FFAR2 signal circuitry programs the cellular identity of enteroendocrine L-cells

In vitro and preclinical literature may discuss cell proliferation, pathway models, or experimental endpoints, but those findings should stay tied to the model being studied

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9, show increases in mitochondrial mass and signalling

In the intestine and brain, PC1 converts proglucagon to the incretin hormones, glucagon-like peptide 1 (GLP-1) and glucagon-like peptide 2 (GLP-2)