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In normal subjects: GHRH alone: GH secretion of 483.7 GHRP-6 alone: GH secretion of 1434.8 GHRH plus GHRP-6: GH secretion of 3771.5 The combined output is not 1918.5 (the additive sum)

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When calcium levels decline (whether from inadequate intake, increased losses, or accelerated bone turnover), parathyroid hormone (PTH) activates as an emergency response, defending serum calcium through bone mobilization, reduced urinary loss, and increased intestinal absorption

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