In addition to reprogramming techniques, emerging rejuvenation modalities include miRNA-loaded exosomes, telomere-activating small molecules, and stem cell transplantation, each of which has the potential to reverse aging phenotypes through distinct mechanisms
Consequently, dysregulation of GSH production is seen in a number of medical conditions, such as renal failure 20 , liver injury 21 , diabetes, neurological diseases 22 , organ fibrosis 23 , and cardiovascular disease 24
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JAMA 334, 6478
Whether definitive biomarkers of ferroptosis can be identified in the future could prove invaluable in studying the biological function of ferroptosis