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More weight loss, better blood sugar control : Clinical trials show Mounjaro may lead to up to 2021% weight loss, and larger A1C reductions than semaglutide

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In 2023 the firm abandoned development of lotiglipron after trial participants showed elevated liver enzymes, and the same year discontinued a twice-daily danuglipron dosing regime after almost three quarters of treated patients experienced nausea, while almost a half developed vomiting and a quarter diarrhoea

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