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M., Melnikova, T

In a forced swimming test, a reduction of the immobility time in bpc 157 (10 microg, 10 ng x kg(-1) i.p.) treated rats corresponds to the activity of the 15 mg or 40 mg (i.p.) of conventional antidepressants, imipramine or nialamide, respectively, given according to the original porsolts protocol

This makes IV therapy a highly efficient form of treatment, especially when compared to other forms of medication delivery

413 Partial ablation of astrocytes in the prefrontal cortex of healthy rats (by injection of gliotoxin L--aminoadipic acid) resulted in the development of depressive-like behaviours, whereas injection of neurotoxin ibotenate did not have such an effect

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Judk P, Esposito S, Coppieters G, Van Eenoo P, Deventer K