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In adults with overweight or obesity (without diabetes) the semaglutide 2.4 mg dose produced an average weight reduction of about 15% of baseline body weight over ~68 weeks in the STEP 1 trial, a result that surprised many clinicians because it brought pharmacologic outcomes into a range previously associated with surgical interventions

Deuxime recommandation : les analogues du GLP-1 doivent tre proposs en complment d'interventions comportementales intensives (alimentation, activit physique , accompagnement)

Some GLP-1 receptor agonists have demonstrated cardiovascular benefits in people with type 2 diabetes at high cardiovascular risk

March 8, 2024

Most GLP-1 medications provide guidance for missed doses in the prescribing information

User reviews suggest some people notice mild appetite changes within a few weeks, while others report no effects even after extended use