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[DOI] [PMC free article] [PubMed] [Google Scholar] 120.Koren S, DiPilato LM, Emmett MJ, Shearin AL, Chu Q, Monks B, et al
BPC-157 works by enhancing fibroblast migration, promoting collagen synthesis, and stimulating angiogenesis (new blood vessel formation) at the injury site
This cytoskeletal stabilization is thought to contribute to its observed effects on tendon and ligament healing in animal models, where organized collagen deposition and tissue strength are paramount
As discussed above, PKA also phosphorylates perilipin on the lipid droplet, resulting in changes that enhance stimulated lipolysis, including movement of perilipin away from the lipid droplet (21), perilipin-mediated remodeling of lipid droplets that increases the surface area available for lipolytic attack (75), and perilipin-mediated activation of HSL activity at the surface of the lipid droplet (84, 125)
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