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These developments illustrate how lifestyle interventions, metabolic surgery, and diabetes medications together form an expanding therapeutic toolkit for MASLD in the context of T2DM (252255)

The two medicines act differently to manage blood sugar

Say good-bye to hunger pangs

Some people are now microdosing GLP-1 drugs, often through compounded versions, as a cheaper or gentler option

Dual GLP-1/GIP agonism is already employed in tirzepatide (Mounjaro), which is authorised in the UK by the MHRA for both type 2 diabetes and weight management

The elimination half-life of the intact GLP-1, including the DPP-4-generated metabolites, such as GLP-1 [936] or GLP-1 [937]) is 2 min