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Regarding ideal body weight, both groups were comparable with mean values of 74.82 7.57 kg in the IGB only group and 74.45 6.30 kg in the IGB + semaglutide group ( p = 0.866)

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Immediate medical attention (via NHS 111 or emergency services) is required if patients develop: Severe, persistent abdominal pain (possible pancreatitis) Marked reduction in urine output or complete cessation Confusion or altered consciousness Severe allergic reactions (rash, difficulty breathing, facial swelling) Healthcare professionals should establish clear safety-netting arrangements , ensuring patients understand when and how to seek help