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For instance, pembrolizumab (for certain cancers) had an ICER of ~$236k/QALY, beyond ICERs range ( [44] )

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doi: 10.1108/IJPSM-06-2021-0145/FULL/PDF 217 RuiuML

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Giurgiuca A, Nemes B, Schipor S, Caragheorgheopol A, Boscaiu V, Cozman D, et al

These effects can be reversed by ferroptosis inhibitors DFO and Fer-1, 110 indicating that the combination of cetuximab and -elemene inhibits EMT by promoting ferroptosis