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Constipation on GLP-1 Therapy: Why It Should Not Be Ignored Constipation is more than an inconvenience

2026 (online)

Since, studies have attempted to elucidate the mechanisms governing this reduction and further identify the clinical utility of GLP-1RAs, but much must be inferred from preclinical studies in diabetic models

The strategies that help constipation from tirzepatide and constipation from semaglutide can make diarrhea worse if applied at the wrong time, and vice versa

These symptoms led to the discontinuation of treatment in 37% of those patients 6