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Description

Gratia, M

Cases like this remind us that animal studies, however promising, cannot predict what will happen when a drug enters the human body

Indeed, both CAR T cells and tumor-infiltrating lymphocytes subjected to a signaling rest via BRAF/MEK 26 and tyrosine kinase inhibitors 27 , respectively, underwent reprogramming associated with improved in vivo expansion

This will be a central focus of the FDA review