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Interestingly, an alternative theoretical model for creatine-dependent thermogenesis has been proposed, which resembles its canonical role in skeletal muscle and other tissues of high energy expenditure 45 , as a fast energy provider for Ca 2+ reuptake into the endoplasmic reticulum 39
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Cognitive Function and Brain Health Acetyl-L-carnitine (ALCAR), the acetylated form of L-Carnitine that readily crosses the blood-brain barrier, demonstrates significant effects on cognitive function and neural health through multiple mechanisms including enhancement of mitochondrial function, modulation of neurotransmitter systems, and reduction of oxidative stress
