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The biochemical characterization of D2L2AD includes a finding of moderately elevated levels of both D-2-HG and L-2-HG in urine, mild increases of both metabolites in the blood, and a very slight elevation of D-2-HG in CSF with normal CSF levels of L-2-HG

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MRP4 MRP4 is a widely versatile transporter that exhibits high substrate specificity composed of a wide variety of amphipathic anions, including steroid and eicosanoid conjugates, as well as cyclic nucleotides and nucleotide analogs

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