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C., Baynes, J

Concurrently, the antinuclear antibody (ANA) titer was 1:100 (homogeneous and cytoplasmic patterns), while routine hematologic parameters were unremarkable

That means the difference between 5mg and 15mg maintenance doses is roughly 6.5 additional percentage points of weight loss, a meaningful but not enormous gap that should factor into conversations with your provider about target dose

Glutamine-dependent changes in gene expression and protein activity

This usually happens when there is a lack of glucose, such as during fasting, a low-carbohydrate diet, or uncontrolled diabetes