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The synovium can secrete proinflammatory cytokines, leading to cartilage damage

The RNA-binding protein SYNCRIP is a component of the hepatocyte exosomal machinery controlling MicroRNA sorting

Common symptoms include heavy menstrual bleeding (menorrhagia), iron deficiency anemia from blood loss, pelvic pressure or pain, abdominal distension, bladder frequency or incomplete emptying (anterior fibroids), constipation or rectal pressure (posterior fibroids), menstrual clotting, and, in some cases, recurrent pregnancy loss or difficulty conceiving

DOI: 10.1111/jdi.12493

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