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The data comes from an open, anonymous platform, where researchers cant verify who is posting or whether users are accurately reporting medication use or symptoms, says Dr

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GLP-1 RAs not only ameliorate insulin resistance and microvascular injury [84], which are significant determinants of depression in T2DM, but also enhance dopamine metabolism and stimulate growth factor signaling pathways, suggesting potential neuroprotective functions [85,86]

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In line with this study, in a double-blind, placebo-controlled RCT enrolling PCOS women with BMI 25 kg/m 2 , Nylander et al