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But in a few days, you might be able to feel pleasure again (although its important to note that stimulant misuse can lead to brain changes and long-term anhedonia as well)
Figure reproduced from Figure 4 of Pabel S et al (2021) under open access creative commons guidelines
Besides the fact that you should inject Zepbound once per week on the same day, there are no other specific guidelines about the best time to use Zepbound
Take a medical approach to weight loss and lose 10-15% of your body weight in one year
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