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Additionally, chronic low-dose exposure, especially in vulnerable populations, has raised concerns about neurodevelopmental disorders, cognitive impairments, and the proliferation of antimicrobial resistance (AMR), a major global health threat that complicates infectious disease treatment and control

Cell 59 , 21012117 (2024)

Despite causing an increased susceptibility to OS, G6PD deficiency may also protect against CVD, since NADPH is an essential cofactor for enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA R), and G6PD deficiency or NADPH deficiency may restrain HMG-CoA R activity similarly to statins (Fig

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