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T., and Schenken J

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This distinction is relevant when considering mitophagy-oriented strategies, because beneficial effects observed after suppression of downstream inflammatory mediators do not by themselves establish that direct augmentation of mitophagy in PACs would remain advantageous under all pathological conditions

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To this end, innovators are exploring two fundamental therapeutic approaches to preserve or improve muscle: Therapies directly acting on muscle growth to mitigate the effect of incretin-based AOMs