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The results showed a 12.3% extension of maximum lifespan in comparison to the control group with no changes to food consumption or body weight

Others argue that as long as high-cost drugs exist, utilization management (UM) is necessary, and ePA is the ethical approach to implement UM transparently and fairly

If the experiment is not carried out immediately, the samples can be kept at -80oC for 1 month

In preclinical studies, FXR agonists, such as obeticholic acid, have been approved for the treatment of primary biliary cholangitis and have shown promising therapeutic potential in intestinal diseases like IBD, although their side effects and tissue specificity require further optimization [474, 475]

It has four main functions: anti-melanogenic, antioxidant, detoxifying, and strengthening the immune system