The primary outcome was percentage total weight loss, with safety among secondary outcomes
Some people need it for a long time to keep the weight off, while others only need it for a short time
Clinical research links psyllium husk intake to better metabolic outcomes, including reduced fasting blood sugar, improved insulin sensitivity, and modest, sustainable weight changes
Food and water were available ad libitum, and mice were held at 12/12 h light/dark cycle at 2023 C and 4060% humidity in standard individually ventilated cages (56 animals in each cage)
Despite this broad therapeutic interest, certain domainsparticularly skeletal muscle biology and neurodegenerationillustrate a recurring translational mismatch between mechanistic signaling effects and clinical functional outcomes
The role of the insulin-like growth factor 1 (IGF-1) in skeletal muscle physiology