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Sirtuins (SIRTs) represent a family of evolutionarily conserved enzymes that are dependent on NAD + , categorized into seven distinct members (SIRT1 through SIRT7) (Wan and Garg, 2021

Treat it as a starting framework, not a rigid prescription

Vivonex and FreAmine III do not contain cysteine

The Zr released from Mn-MOF downregulated GSH efficiently (Figure 5G), thus elevating Mn-MOF-induced ROS concentration, leading to the deactivation of GPX4 and ROS-enhanced ferroptosis

Daily application at roughly the same time produces better results than sporadic use even at higher doses

Sections were coverslipped with neutral balsam (Beyotime) and air-dried