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Tirzepatide (Mounjaro, Zepbound) is an FDA-approved medication for type 2 diabetes and chronic weight management that works by activating both GIP and GLP-1 receptors

For this reason, its been used to help enhance athletic performance, fight fatigue, and provide additional energy to get through hectic schedules

In addition, the application of exendin-4, a GLP-1RA in obese mice triggered by diet restores C1q/TNF-related protein 3 (CTRP3) expression in keratinocytes, thereby inhibiting STAT3 phosphorylation via lysosomal-associated membrane protein 1 (LAMP1) and alleviating the psoriatic symptoms induced by imiquimod treatment [204]

More serious potential risks include pancreatitis, gallbladder disease, and hypoglycemia when used with other glucose-lowering medications