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In addition, sulforaphane has been shown to activate the Nrf2 pathway, a critical regulator of cellular defense mechanisms

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Interestingly, the prenatal inhibition of GABAergic signaling with GABA receptor antagonists, such as picrotoxin administration on E10-12, suppressed neurogenesis in the fetal brain (97) and resulted in ASD-like social deficits in offspring (97, 98)

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