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Moderate-Quality Evidence), SGLT2i to reduce the risk of hospitalization for HF or the composite of significant decline in eGFR, progression to end-stage kidney disease or kidney death (Strong Recommendation

Loss of muscle leads to a lower resting metabolic rate, reduced physical strength, and a higher risk of injury or frailty in older adults

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Research use only not for human consumption

doi: 10.1681/ASN.2011121159 39 MatsusakaTNiimuraFPastanIShintaniANishiyamaAIchikawaI

Side effects like nausea can increase dehydration risk, and suppressed appetite sometimes makes it easy to forget to drink enough