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While these costs are generally modest, they add up over time and should be factored into the overall treatment budget

It is not listed on WADA's Prohibited List, as it is not considered to have performance-enhancing properties relevant to competitive sport

The SIRT3/FOXO3 axis upregulates the PINK1/PARKIN axis to increase mitophagy when SIRT3 expression is increased 99

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However, studies using 3D-serial electron microscopy demonstrated that dendritic ER has many contact sites with mitochondria (MAMs, mitochondria-associated membranes) [60]

10.1161/CIRCIMAGING.109.899377